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Brain Endothelial Cells Synthesize Neurotoxic Thrombin in Alzheimer’s Disease
Alzheimer’s disease (AD) is characterized by neuronal death; thus, identifying neurotoxic proteins and their source is central to understanding and treating AD. The multifunctional protease thrombin is neurotoxic and found in AD senile plaques. The objective of this study was to determine whether br...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843451/ https://ncbi.nlm.nih.gov/pubmed/20150433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090406 |
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