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Brain Endothelial Cells Synthesize Neurotoxic Thrombin in Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by neuronal death; thus, identifying neurotoxic proteins and their source is central to understanding and treating AD. The multifunctional protease thrombin is neurotoxic and found in AD senile plaques. The objective of this study was to determine whether br...

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Hlavní autoři: Yin, Xiangling, Wright, Jill, Wall, Trevor, Grammas, Paula
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843451/
https://ncbi.nlm.nih.gov/pubmed/20150433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090406
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