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Binding of Curcumin and its Long Chain Derivatives to the Activator Binding Domain of Novel Protein Kinase C
Protein Kinase C (PKC) is a family of serine/threonine kinases that play a central role in cellular signal transduction. The second messenger diacylglycerol having two long carbon chains acts as the endogenous ligand for the PKCs. Polyphenol curcumin, the active constituent of Curcuma longa is an an...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843403/ https://ncbi.nlm.nih.gov/pubmed/20100661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.12.075 |
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