In vitro activities of fleroxacin against clinical isolates of Legionella spp., its pharmacokinetics in guinea pigs, and use to treat guinea pigs with L. pneumophila pneumonia.

The activities of fleroxacin against 22 clinical Legionella isolates were determined by agar and broth microdilution susceptibility testing. The fleroxacin MIC required to inhibit 90% of strains tested on buffered charcoal yeast extract agar medium supplemented with 0.1% alpha-ketoglutarate was 0.64...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Edelstein, P H, Edelstein, M A, Holzknecht, B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284340/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1489182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.11.2387
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