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Global Conformational Change Associated with the Two-step Reaction Catalyzed by Escherichia coli Lipoate-Protein Ligase A

Lipoate-protein ligase A (LplA) catalyzes the attachment of lipoic acid to lipoate-dependent enzymes by a two-step reaction: first the lipoate adenylation reaction and, second, the lipoate transfer reaction. We previously determined the crystal structure of Escherichia coli LplA in its unliganded fo...

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Detalhes bibliográficos
Main Authors: Fujiwara, Kazuko, Maita, Nobuo, Hosaka, Harumi, Okamura-Ikeda, Kazuko, Nakagawa, Atsushi, Taniguchi, Hisaaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843243/
https://ncbi.nlm.nih.gov/pubmed/20089862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078717
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