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Fat-specific Protein 27 Undergoes Ubiquitin-dependent Degradation Regulated by Triacylglycerol Synthesis and Lipid Droplet Formation

The fat-specific protein 27 (Fsp27), a protein localized to lipid droplets (LDs), plays an important role in controlling lipid storage and mitochondrial activity in adipocytes. Fsp27-null mice display increased energy expenditure and are resistant to high fat diet-induced obesity and diabetes. Howev...

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Detalhes bibliográficos
Main Authors: Nian, Zongqian, Sun, Zhiqi, Yu, Luxin, Toh, Shen Yon, Sang, Jianli, Li, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843210/
https://ncbi.nlm.nih.gov/pubmed/20089860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043786
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