HDAC6-mediated acetylation of lipid droplet–binding protein CIDEC regulates fat-induced lipid storage

Obesity is characterized by aberrant fat accumulation. However, the intracellular signaling pathway that senses dietary fat and leads to fat storage remains elusive. Here, we have observed that the levels of histone deacetylase 6 (HDAC6) and the related family member HDAC10 are markedly reduced in a...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Qian, Hui, Chen, Yuanying, Nian, Zongqian, Su, Lu, Yu, Haoyong, Chen, Feng-Jung, Zhang, Xiuqin, Xu, Wenyi, Zhou, Linkang, Liu, Jiaming, Yu, Jinhai, Yu, Luxin, Gao, Yan, Zhang, Hongchao, Zhang, Haihong, Zhao, Shimin, Yu, Li, Xiao, Rui-Ping, Bao, Yuqian, Hou, Shaocong, Li, Pingping, Li, Jiada, Deng, Haiteng, Jia, Weiping, Li, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373879/
https://ncbi.nlm.nih.gov/pubmed/28287402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85963
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky