HDAC6-mediated acetylation of lipid droplet–binding protein CIDEC regulates fat-induced lipid storage

Obesity is characterized by aberrant fat accumulation. However, the intracellular signaling pathway that senses dietary fat and leads to fat storage remains elusive. Here, we have observed that the levels of histone deacetylase 6 (HDAC6) and the related family member HDAC10 are markedly reduced in a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Qian, Hui, Chen, Yuanying, Nian, Zongqian, Su, Lu, Yu, Haoyong, Chen, Feng-Jung, Zhang, Xiuqin, Xu, Wenyi, Zhou, Linkang, Liu, Jiaming, Yu, Jinhai, Yu, Luxin, Gao, Yan, Zhang, Hongchao, Zhang, Haihong, Zhao, Shimin, Yu, Li, Xiao, Rui-Ping, Bao, Yuqian, Hou, Shaocong, Li, Pingping, Li, Jiada, Deng, Haiteng, Jia, Weiping, Li, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373879/
https://ncbi.nlm.nih.gov/pubmed/28287402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85963
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