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The Mouse Immunoglobulin Heavy Chain V-D Intergenic Sequence Contains Insulators That May Regulate Ordered V(D)J Recombination

During immunoglobulin heavy chain (Igh) V(D)J recombination, D to J precedes V to DJ recombination in an ordered manner, controlled by differential chromatin accessibility of the V and DJ regions and essential for correct antibody assembly. However, with the exception of the intronic enhancer Eμ, wh...

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Autori principali: Featherstone, Karen, Wood, Andrew L., Bowen, Adam J., Corcoran, Anne E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843181/
https://ncbi.nlm.nih.gov/pubmed/20100833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098251
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