V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer.

Ítems similars

• The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate.
  per: Fernex, C, et al.
  Publicat: (1995)
• A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation
  per: Chakraborty, Tirtha, et al.
  Publicat: (2009)
• Immunoglobulin heavy chain gene rearrangement involving V-V region recombination.
  per: Deane, M, et al.
  Publicat: (1990)
• Deletion of the IgH enhancer does not reduce immunoglobulin heavy chain production of a hybridoma IgD class switch variant.
  per: Klein, S, et al.
  Publicat: (1984)
• Expression of the (recombinant) endogenous immunoglobulin heavy-chain locus requires the intronic matrix attachment regions.
  per: Oancea, A E, et al.
  Publicat: (1997)