Revelation of p53-independent Function of MTA1 in DNA Damage Response via Modulation of the p21(WAF1)-Proliferating Cell Nuclear Antigen Pathway

Although metastasis-associated protein 1 (MTA1), a component of the nucleosome remodeling and deacetylase (NuRD) complex, is a DNA-damage response protein and regulates p53-dependent DNA repair, it remains unknown whether MTA1 also participates in p53-independent DNA damage response. Here, we provid...

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Autori principali: Li, Da-Qiang, Pakala, Suresh B., Reddy, Sirigiri Divijendra Natha, Ohshiro, Kazufumi, Peng, Shao-Hua, Lian, Yi, Fu, Sidney W., Kumar, Rakesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843167/
https://ncbi.nlm.nih.gov/pubmed/20071335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079095
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