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Axonal Mitochondrial Clusters Containing Mutant SOD1 in Transgenic Models of ALS

We studied the subcellular distribution of mitochondria and superoxide dismutase-1 (SOD1) in whole mounts of microdissected motor axons of rats expressing the ALS-linked SOD1-G93A mutation. The rationale was to determine whether physical interactions between the enzyme and mitochondria were linked t...

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Detalhes bibliográficos
Main Authors: Sotelo-Silveira, Jose R., Lepanto, Paola, Elizondo, Victoria, Horjales, Sofia, Palacios, Florencia, Martinez-Palma, Laura, Marin, Monica, Beckman, Joseph S., Barbeito, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842590/
https://ncbi.nlm.nih.gov/pubmed/19344250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2614
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