T-cell exhaustion: characteristics, causes and conversion

T-cell exhaustion is characterized by the stepwise and progressive loss of T-cell functions and can culminate in the physical deletion of the responding cells. Exhaustion is well-defined during chronic lymphocytic choriomeningitis virus infection and commonly develops under conditions of antigen-per...

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Bibliografiske detaljer
Main Authors: Yi, John S, Cox, Maureen A, Zajac, Allan J
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2010
Fag:
Review articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842494/
https://ncbi.nlm.nih.gov/pubmed/20201977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03255.x
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