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“Unlicensed” Natural Killer cells dominate the response to cytomegalovirus infection
Natural killer (NK) cells expressing inhibitory receptors that bind to self-MHC class I are “licensed” or rendered functionally more responsive to stimulation, whereas “unlicensed” NK cells lacking receptors for self-MHC class I are hyporesponsive. Here we show that, contrary to the licensing hypoth...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842453/ https://ncbi.nlm.nih.gov/pubmed/20190757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1849 |
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