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Ly49H signaling through DAP10 is essential for optimal natural killer cell responses to mouse cytomegalovirus infection

The activating natural killer (NK) cell receptor Ly49H recognizes the mouse cytomegalovirus (MCMV) m157 glycoprotein expressed on the surface of infected cells and is required for protection against MCMV. Although Ly49H has previously been shown to signal via DAP12, we now show that Ly49H must also...

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Detalhes bibliográficos
Main Authors: Orr, Mark T., Sun, Joseph C., Hesslein, David G.T., Arase, Hisashi, Phillips, Joseph H., Takai, Toshiyuki, Lanier, Lewis L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715124/
https://ncbi.nlm.nih.gov/pubmed/19332875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090168
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