Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells, but not in pericytes

RATIONALE: Pathological neovascularization is a critical component of diseases such as proliferative retinopathies, cancer and rheumatoid arthritis, yet much remains to be learned about the underlying causes. Previous studies showed that VEGF-A activates the membrane-anchored metalloproteinase ADAM1...

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Auteurs principaux: Weskamp, Gisela, Mendelson, Karen, Swendeman, Steve, Le Gall, Sylvain, Ma, Yan, Lyman, Stephen, Hinoki, Akinari, Eguchi, Satoru, Guaiquil, Victor, Horiuchi, Keisuke, Blobel, Carl P.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842448/
https://ncbi.nlm.nih.gov/pubmed/20110534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.207415
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