BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer

BACKGROUND: The BMI1 oncogene is overexpressed in several human malignancies including gastric cancer. In addition to BMI1, mammalian cells also express Mel-18, which is closely related to BMI1. We have reported that Mel-18 functions as a potential tumor suppressor by repressing the expression of BM...

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Huvudupphovsmän: Zhang, Xiao-Wei, Sheng, Ya-Ping, Li, Qian, Qin, Wei, Lu, You-Wei, Cheng, Yu-Fan, Liu, Bing-Ya, Zhang, Feng-Chun, Li, Jin, Dimri, Goberdhan P, Guo, Wei-Jian
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842237/
https://ncbi.nlm.nih.gov/pubmed/20170541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-40
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