Reassortment between avian H5N1 and human H3N2 influenza viruses creates hybrid viruses with substantial virulence

The spread of avian H5N1 influenza viruses around the globe has become a worldwide public health concern. To evaluate the pathogenic potential of reassortant viruses between currently cocirculating avian H5N1 and human H3N2 influenza viruses, we generated all the 254 combinations of reassortant viru...

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Main Authors: Li, Chengjun, Hatta, Masato, Nidom, Chairul A., Muramoto, Yukiko, Watanabe, Shinji, Neumann, Gabriele, Kawaoka, Yoshihiro
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842136/
https://ncbi.nlm.nih.gov/pubmed/20176961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912807107
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