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Role of host-specific amino acids in the pathogenicity of avian H5N1 influenza viruses in mice

Recent large-scale sequence analyses revealed ‘signature’ amino acids at specific positions in viral proteins that distinguish human influenza viruses from avian viruses. To determine the role of these host lineage-specific amino acids in the pathogenicity of H5N1 avian influenza viruses, we generat...

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Bibliografski detalji
Glavni autori: Kim, Jin Hyun, Hatta, Masato, Watanabe, Shinji, Neumann, Gabriele, Watanabe, Tokiko, Kawaoka, Yoshihiro
Format: Artigo
Jezik:Inglês
Izdano: Society for General Microbiology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878586/
https://ncbi.nlm.nih.gov/pubmed/20016035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.018143-0
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