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Origins of catalysis by computationally designed retroaldolase enzymes

We have investigated recently reported computationally designed retroaldolase enzymes with the goal of understanding the extent and the origins of their catalytic power. Direct comparison of the designed enzymes to primary amine catalysts in solution revealed a rate acceleration of 10(5)-fold for th...

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Detaylı Bibliyografya
Asıl Yazarlar: Lassila, Jonathan K., Baker, David, Herschlag, Daniel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841948/
https://ncbi.nlm.nih.gov/pubmed/20194782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913638107
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