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Conformational diversity and computational enzyme design
The application of computational protein design methods to the design of enzyme active sites offers potential routes to new catalysts and new reaction specificities. Computational design methods have typically treated the protein backbone as a rigid structure for the sake of computational tractabili...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953567/ https://ncbi.nlm.nih.gov/pubmed/20829099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.08.010 |
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