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Engineering cis-telomerase RNAs that add telomeric repeats to themselves
Telomerase is a ribonucleoprotein complex consisting of a protein reverse transcriptase (TERT) and an RNA subunit (TR). Telomerase normally adds telomeric DNA repeats to chromosome ends. Here, we engineer human and Tetrahymena cis-telomerase RNAs, each having a DNA primer covalently linked to its 3′...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841905/ https://ncbi.nlm.nih.gov/pubmed/20194781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909366107 |
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