Llwytho...

Engineering cis-telomerase RNAs that add telomeric repeats to themselves

Telomerase is a ribonucleoprotein complex consisting of a protein reverse transcriptase (TERT) and an RNA subunit (TR). Telomerase normally adds telomeric DNA repeats to chromosome ends. Here, we engineer human and Tetrahymena cis-telomerase RNAs, each having a DNA primer covalently linked to its 3′...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Qiao, Feng, Goodrich, Karen J., Cech, Thomas R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841905/
https://ncbi.nlm.nih.gov/pubmed/20194781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909366107
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