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Pore architecture of the ORAI1 store-operated calcium channel
ORAI1 is the pore-forming subunit of the calcium release-activated calcium (CRAC) channel, a store-operated channel that is central to Ca(2+) signaling in mammalian cells. Electrophysiological data have shown that the acidic residues E106 in transmembrane helix 1 (TM1) and E190 in TM3 contribute to...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841875/ https://ncbi.nlm.nih.gov/pubmed/20194792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001169107 |
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