ImmunoPET imaging of B-cell lymphoma using (124)I-anti-CD20 scFv dimers (diabodies)

Rapid clearing engineered antibody fragments for immunoPET promise high sensitivity at early time points. Here, tumor targeting of anti-CD20 diabodies (scFv dimers) for detection of low-grade B-cell lymphomas were evaluated. In addition, the effect of linker length on oligomerization of the diabody...

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Bibliografiska uppgifter
Huvudupphovsmän: Olafsen, Tove, Sirk, Shannon J., Betting, David J., Kenanova, Vania E., Bauer, Karl B., Ladno, Waldemar, Raubitschek, Andrew A., Timmerman, John M., Wu, Anna M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
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Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841542/
https://ncbi.nlm.nih.gov/pubmed/20053640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzp081
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