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ImmunoPET imaging of B-cell lymphoma using (124)I-anti-CD20 scFv dimers (diabodies)
Rapid clearing engineered antibody fragments for immunoPET promise high sensitivity at early time points. Here, tumor targeting of anti-CD20 diabodies (scFv dimers) for detection of low-grade B-cell lymphomas were evaluated. In addition, the effect of linker length on oligomerization of the diabody...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841542/ https://ncbi.nlm.nih.gov/pubmed/20053640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzp081 |
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