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Mitochondrial autophagy as a compensatory response to PINK1 deficiency
Macroautophagy (hereafter, autophagy) plays a critical role in maintaining cellular homeostasis by degrading protein aggregates and dysfunctional/damaged organelles. We recently reported that silencing the recessive familial Parkinson disease gene encoding PTEN-induced kinase 1 (PINK1) leads to neur...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2009
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841445/ https://ncbi.nlm.nih.gov/pubmed/19786829 |
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