Biodistributions of (177)Lu- and (111)In- labeled 7E11 Antibodies to Prostate-Specific Membrane Antigen in Xenograft Model of Prostate Cancer and Potential Use of (111)In-7E11 as a Pretherapeutic Agent for (177)Lu-7E11 Radioimmunotherapy

Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein highly expressed in many prostate cancers, and can be targeted with radiolabeled antibodies for diagnosis and treatment of this disease. To serve as a radioimmunotherapeutic agent, a kinetically inert conjugate is desired to m...

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Main Authors: Pan, Mei-Hsiu, Gao, Dong-Wei, Feng, Jinjin, He, Jiang, Seo, Youngho, Tedesco, John, Wolodzko, John G., Hasegawa, Bruce H., Franc, Benjamin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841328/
https://ncbi.nlm.nih.gov/pubmed/19034582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-008-0185-9
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