Pretargeted Radioimmunotherapy of Prostate Cancer with an Anti-TROP-2×Anti-HSG Bispecific Antibody and a (177)Lu-Labeled Peptide

TROP-2 is a pancarcinoma marker that is expressed at high levels in many epithelial cancers, including prostate cancer (PC). The trivalent bispecific antibody TF12 (anti-TROP2×anti-HSG [histamine-succinyl-glycine]) has shown to effectively target PC. In this study, the efficacy of pretargeted radioi...

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Main Authors: van Rij, Catharina M., Frielink, Cathelijne, Goldenberg, David M., Sharkey, Robert M., Lütje, Susanne, McBride, William J., Oyen, Wim J.G., Boerman, Otto C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186637/
https://ncbi.nlm.nih.gov/pubmed/25226447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2014.1660
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