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Gold(I)-Catalyzed Hydroarylation of Allenes with Indoles

Reaction of a monosubstituted, 1,3-disubstituted, or tetrasubstituted allene with various indoles catalyzed by a 1:1 mixture of a gold(I) N-heterocyclic carbene complex and AgOTf at room temperature leads to hydroarylation with formation of 3-allyl-indoles in modest to good yield.

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Detalhes bibliográficos
Main Authors: Toups, Kristina L., Liu, Gordon T., Widenhoefer, Ross A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841298/
https://ncbi.nlm.nih.gov/pubmed/20305794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jorganchem.2008.11.058
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