Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system

BACKGROUND: After a spinal cord lesion, axon regeneration is inhibited by the presence of a diversity of inhibitory molecules in the lesion environment. At and around the lesion site myelin-associated inhibitors, chondroitin sulfate proteoglycans (CSPGs) and several axon guidance molecules, includin...

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Hlavní autoři: Ehlert, Erich M, Eggers, Ruben, Niclou, Simone P, Verhaagen, Joost
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841193/
https://ncbi.nlm.nih.gov/pubmed/20167052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-20
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