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Long-Term Adeno-Associated Viral Vector-Mediated Expression of Truncated TrkB in the Adult Rat Facial Nucleus Results in Motor Neuron Degeneration

Adult facial motor neurons continue to express full-length TrkB tyrosine kinase receptor (TrkB.FL), the high-affinity receptor for the neurotrophins BDNF and neurotrophic factor-4/5 (NT-4/5), suggesting that they remain dependent on target-derived and locally produced neurotrophins in adulthood. Stu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: De Wit, Joris, Eggers, Ruben, Evers, Robert, Castrén, Eero, Verhaagen, Joost
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675476/
https://ncbi.nlm.nih.gov/pubmed/16452675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4543-05.2006
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