Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

BACKGROUND: Inactivating genes in vivo is an important technique for establishing their function in the adult nervous system. Unfortunately, conventional knockout mice may suffer from several limitations including embryonic or perinatal lethality and the compensatory regulation of other genes. One a...

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Hlavní autoři: Ahmed, Bushra Y, Chakravarthy, Sridhara, Eggers, Ruben, Hermens, Wim TJMC, Zhang, Jing Ying, Niclou, Simone P, Levelt, Christiaan, Sablitzky, Fred, Anderson, Patrick N, Lieberman, AR, Verhaagen, Joost
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC343275/
https://ncbi.nlm.nih.gov/pubmed/15005815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-5-4
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