Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

BACKGROUND: Inactivating genes in vivo is an important technique for establishing their function in the adult nervous system. Unfortunately, conventional knockout mice may suffer from several limitations including embryonic or perinatal lethality and the compensatory regulation of other genes. One a...

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Pubblicato in:	BMC Neurosci
Autori principali:	Ahmed, Bushra Y, Chakravarthy, Sridhara, Eggers, Ruben, Hermens, Wim TJMC, Zhang, Jing Ying, Niclou, Simone P, Levelt, Christiaan, Sablitzky, Fred, Anderson, Patrick N, Lieberman, AR, Verhaagen, Joost
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2004
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15005815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2202-5-4
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