Selective regain of egfr gene copies in CD44(+)/CD24(-/low )breast cancer cellular model MDA-MB-468

BACKGROUND: Increased transcription of oncogenes like the epidermal growth factor receptor (EGFR) is frequently caused by amplification of the whole gene or at least of regulatory sequences. Aim of this study was to pinpoint mechanistic parameters occurring during egfr copy number gains leading to a...

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Detalhes bibliográficos
Main Authors: Agelopoulos, Konstantin, Greve, Burkhard, Schmidt, Hartmut, Pospisil, Heike, Kurtz, Stefan, Bartkowiak, Kai, Andreas, Antje, Wieczorek, Marek, Korsching, Eberhard, Buerger, Horst, Brandt, Burkhard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841141/
https://ncbi.nlm.nih.gov/pubmed/20199686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-78
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