Selective regain of egfr gene copies in CD44(+)/CD24(-/low )breast cancer cellular model MDA-MB-468

BACKGROUND: Increased transcription of oncogenes like the epidermal growth factor receptor (EGFR) is frequently caused by amplification of the whole gene or at least of regulatory sequences. Aim of this study was to pinpoint mechanistic parameters occurring during egfr copy number gains leading to a...

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Hauptverfasser: Agelopoulos, Konstantin, Greve, Burkhard, Schmidt, Hartmut, Pospisil, Heike, Kurtz, Stefan, Bartkowiak, Kai, Andreas, Antje, Wieczorek, Marek, Korsching, Eberhard, Buerger, Horst, Brandt, Burkhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841141/
https://ncbi.nlm.nih.gov/pubmed/20199686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-78
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