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Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen
Biological networks are highly complex systems, consisting largely of enzymes that act as molecular switches to activate/inhibit downstream targets via post-translational modification. Computational techniques have been developed to perform signaling network inference using some high-throughput data...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840989/ https://ncbi.nlm.nih.gov/pubmed/20144944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.100248.109 |
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