Leptin Replacement Prevents Weight Loss-Induced Metabolic Adaptation in Congenital Leptin-Deficient Patients

Context: Leptin regulates energy homeostasis by suppressing food intake; however, its role in energy expenditure and fat oxidation remains uncertain in humans. Objective: The aim of the study was to assess 24-h energy metabolism before and after weight loss induced by leptin treatment in congenital...

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Bibliographic Details
Main Authors: Galgani, Jose E., Greenway, Frank L., Caglayan, Sinan, Wong, Ma-Li, Licinio, Julio, Ravussin, Eric
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2010
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840850/
https://ncbi.nlm.nih.gov/pubmed/20061423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-1739
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