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Leptin replacement alters brain response to food cues in genetically leptin-deficient adults
A missense mutation in the ob gene causes leptin deficiency and morbid obesity. Leptin replacement to three adults with this mutation normalized body weight and eating behavior. Because the neural circuits mediating these changes were unknown, we paired functional magnetic resonance imaging (fMRI) w...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084333/ https://ncbi.nlm.nih.gov/pubmed/17986612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706481104 |
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