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Hypothalamic Insulin-Like Growth Factor-I Receptors Are Necessary for Hormone-Dependent Luteinizing Hormone Surges: Implications for Female Reproductive Aging

Brain IGF-I receptors are required for maintenance of estrous cycles in young adult female rats. Circulating and hypothalamic IGF-I levels decrease with aging, suggesting a role for IGF-I in the onset of reproductive senescence. Therefore, the present study investigated potential mechanisms of actio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Todd, Brigitte J., Merhi, Zaher O., Shu, Jun, Etgen, Anne M., Neal-Perry, Genevieve S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Endocrine Society 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840696/
https://ncbi.nlm.nih.gov/pubmed/20097715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1009
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