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Restoration of the Luteinizing Hormone Surge in Middle-Aged Female Rats by Altering the Balance of GABA and Glutamate Transmission in the Medial Preoptic Area

Hypothalamic glutamate and gamma-aminobutyric acid (GABA) neurotransmission are involved in the ovarian hormone-induced GnRH-LH surge in rodents. We previously reported that middle-aged rats have significantly less glutamate release in the medial preoptic area than young rats on the day of the LH su...

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Detalhes bibliográficos
Main Authors: Neal-Perry, Genevieve S., Zeevalk, Gail D., Shu, Jun, Etgen, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714996/
https://ncbi.nlm.nih.gov/pubmed/18667749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.069831
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