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Mice Lacking Hepatic Lipase Are Lean and Protected against Diet-Induced Obesity and Hepatic Steatosis

Hepatic lipase (HL)-mediated lipoprotein hydrolysis provides free fatty acids for energy, storage, and nutrient signaling and may play a role in energy homeostasis. Because HL-activity increases with increased visceral fat, we hypothesized that increased HL-activity favors weight gain and obesity an...

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Detalhes bibliográficos
Main Authors: Chiu, Harvey K., Qian, Kun, Ogimoto, Kayoko, Morton, Gregory J., Wisse, Brent E., Agrawal, Nalini, McDonald, Thomas O., Schwartz, Michael W., Dichek, Helén L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840680/
https://ncbi.nlm.nih.gov/pubmed/20056822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1100
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