In vivo structure-function studies of human hepatic lipase: the catalytic function rescues the lean phenotype of HL-deficient (hl(−/−)) mice

The lean body weight phenotype of hepatic lipase (HL)–deficient mice (hl(−/−)) suggests that HL is required for normal weight gain, but the underlying mechanisms are unknown. HL plays a unique role in lipoprotein metabolism performing bridging as well as catalytic functions, either of which could pa...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Chen, Jeffrey, Kaiyala, Karl J, Lam, Jennifer, Agrawal, Nalini, Nguyen, Lisa, Ogimoto, Kayoko, Spencer, Dean, Morton, Gregory J, Schwartz, Michael W, Dichek, Helén L
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425970/
https://ncbi.nlm.nih.gov/pubmed/25862097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12365
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