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Permeabilizing and hemolytic action of large and small polyene antibiotics on human erythrocytes.

The effects of large polyenes (heptaenes and the "degenerate heptaene" nystatin) on human erythrocytes were found to occur in three separate stages. Stage I was a reversible increase in cell membrane permeability to monovalent cations and occurred at low antibiotic concentrations. At intermediate an...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Brajtburg, J, Medoff, G, Kobayashi, G S, Elberg, S, Finegold, C
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1980
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7447419/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.586
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