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Permeabilizing and hemolytic action of large and small polyene antibiotics on human erythrocytes.

The effects of large polyenes (heptaenes and the "degenerate heptaene" nystatin) on human erythrocytes were found to occur in three separate stages. Stage I was a reversible increase in cell membrane permeability to monovalent cations and occurred at low antibiotic concentrations. At inter...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Brajtburg, J, Medoff, G, Kobayashi, G S, Elberg, S, Finegold, C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7447419/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.586
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