Interference with effects of amphotericin B on Candida albicans cells by 2-chloroethyl-1-nitrosoureas.

Two nitrosoureas, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU), with strong carbamoylating and weak alkylating activities, interfered with the induction of potassium leakage and lethal action of amphotericin B (AmB) on Candida albicans. 2-Cyclo...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Brajtburg, J, Elberg, S, Kobayashi, G S, Medoff, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172169/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3284460/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.3.327
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