Interference with effects of amphotericin B on Candida albicans cells by 2-chloroethyl-1-nitrosoureas.

Two nitrosoureas, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU), with strong carbamoylating and weak alkylating activities, interfered with the induction of potassium leakage and lethal action of amphotericin B (AmB) on Candida albicans. 2-Cyclo...

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Main Authors: Brajtburg, J, Elberg, S, Kobayashi, G S, Medoff, G
格式: Artigo
語言:Inglês
出版: 1988
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC172169/
https://ncbi.nlm.nih.gov/pubmed/3284460
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