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Permeabilizing and hemolytic action of large and small polyene antibiotics on human erythrocytes.

The effects of large polyenes (heptaenes and the "degenerate heptaene" nystatin) on human erythrocytes were found to occur in three separate stages. Stage I was a reversible increase in cell membrane permeability to monovalent cations and occurred at low antibiotic concentrations. At inter...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Brajtburg, J, Medoff, G, Kobayashi, G S, Elberg, S, Finegold, C
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7447419/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.586
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