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Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli

DNA damage occurs continuously, and faithful replication and transcription are essential for maintaining cell viability. Cells in nature are not dividing and replicating DNA often; therefore it is important to consider the outcome of RNA polymerase (RNAP) encounters with DNA damage. Base damage in t...

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書目詳細資料
Main Authors: Clauson, Cheryl L., Oestreich, Kenneth J., Austin, James W., Doetsch, Paul W.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840506/
https://ncbi.nlm.nih.gov/pubmed/20142484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913191107
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