Relationship between metronidazole metabolism and bactericidal activity.
It has been suggested that the microbicidal effect of metronidazole is mediated by an intermediate in nitro group reduction. We have found that the addition of Escherichia coli enhances the lethal effect of metronidazole on Bacillus fragilis and suggest that this intermediate may form in one bacteri...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1980
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284050/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6255861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.566 |
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