Relationship between metronidazole metabolism and bactericidal activity.

It has been suggested that the microbicidal effect of metronidazole is mediated by an intermediate in nitro group reduction. We have found that the addition of Escherichia coli enhances the lethal effect of metronidazole on Bacillus fragilis and suggest that this intermediate may form in one bacteri...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Chrystal, E J, Koch, R L, McLafferty, M A, Goldman, P
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1980
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284050/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6255861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.566
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