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Relationship between metronidazole metabolism and bactericidal activity.

It has been suggested that the microbicidal effect of metronidazole is mediated by an intermediate in nitro group reduction. We have found that the addition of Escherichia coli enhances the lethal effect of metronidazole on Bacillus fragilis and suggest that this intermediate may form in one bacteri...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Chrystal, E J, Koch, R L, McLafferty, M A, Goldman, P
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1980
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6255861/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.566
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