Relationship between metronidazole metabolism and bactericidal activity.

It has been suggested that the microbicidal effect of metronidazole is mediated by an intermediate in nitro group reduction. We have found that the addition of Escherichia coli enhances the lethal effect of metronidazole on Bacillus fragilis and suggest that this intermediate may form in one bacteri...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Chrystal, E J, Koch, R L, McLafferty, M A, Goldman, P
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1980
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284050/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6255861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.566
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